Primary Information
BoMiProt ID	Bomi10206
Protein Name	Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial/Coenzyme Q biosynthesis protein 4 homolog
Organism	Bos taurus
Uniprot ID	Q05B52
Milk Fraction	Whey
Ref Sequence ID	NP_001077141.1
Aminoacid Length	151
Molecular Weight	16337
FASTA Sequence	Download
Gene Name	COQ4
Gene ID	511987
Protein Existence Status	Reviewed
Secondary Information
Protein Function	Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides
PTMs	Phosphorylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q05B52|COQ4_BOVIN Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial OS=Bos taurus OX=9913 GN=COQ4 PE=2 SV=1 MATLLRGVLRPLCAFRGGPGPPAGVPFRAVSHGTGLLYPEHIPTSVLQKVLLAAGSAGMA LYDPYRHDMVAVLGETTGRRTLKVLRDQMKRDPEGAQILQERPRISLS*108TLDMGKLRSLPE GSFGCAYLHFLDVNVASGRGMTVCTEDFIQC
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Laugwitz, L., Seibt, A., Herebian, D., Peralta, S., Kienzle, I., Buchert, R., Falb, R., Gauck, D., Müller, A., Grimmel, M., Beck-Woedel, S., Kern, J., Daliri, K., Katibeh, P., Danhauser, K., Leiz, S., Alesi, V., Baertling, F., Vasco, G., Steinfeld, R., … Distelmaier, F. (2021). Human COQ4 deficiency: delineating the clinical, metabolic and neuroimaging phenotypes. Journal of medical genetics, jmedgenet-2021-107729. Advance online publication. https://doi.org/10.1136/jmedgenet-2021-107729