Primary Information |
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| BoMiProt ID | Bomi10188 |
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| Protein Name | U3 small nucleolar RNA-associated protein 15 homolog |
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| Organism | Bos taurus |
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| Uniprot ID | A7MB12 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | /NP_001094598.1 |
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| Aminoacid Length | 519 |
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| Molecular Weight | 58495 |
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| FASTA Sequence |
Download |
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| Gene Name | UTP15 |
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| Gene ID | 526343 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | WD-repeat containing proteins in human SSU processome components.The SSU processome is a 2.2 MDa ribonucleoprotein complex involved in not only the processing of rRNA but also the assembly and maturation of the SSU of eukaryotic ribosomes.Participate in nucleolar processing of pre-18S ribosomal RNA. |
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| Biochemical Properties | WD-repeats are conserved domains comprising approximately 40–60 amino acids and forms a beta propeller conformation.WD-repeats act as structural platforms for protein–protein interactions. |
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| PTMs | Acetylation, Isopeptide bond formation, Ubl conjugation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | no TM helices |
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| Additional Comments | found in the nuclear matrix fraction of HeLa cells |
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| Bibliography | Wada K, Sato M, Araki N, Kumeta M, Hirai Y, Takeyasu K, Furukawa K, Horigome T. Dynamics of WD-repeat containing proteins in SSU processome components. Biochem Cell Biol. 2014 Jun;92(3):191-9. doi: 10.1139/bcb-2014-0007. Epub 2014 Mar 27. PMID: 24754225. |
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