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BoMiProt ID - Bomi10142
Primary Information
BoMiProt ID
Bomi10142
Protein Name
Tumor necrosis factor alpha-induced protein 8
Organism
Bos taurus
Uniprot ID
A4IF78
Milk Fraction
Exosomes
Ref Sequence ID
NP_001077180.1
Aminoacid Length
198
Molecular Weight
22995
FASTA Sequence
Download
Gene Name
TNFAIP8
Gene ID
529336
Protein Existence Status
reviewed
Secondary Information
Protein Function
Acts as a negative mediator of apoptosis. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Site(s) of PTM(s)
N-glycosylation
,
O-glycosylation
,
Phosphorylation
na
Predicted Disorder Regions
1-15, 24-37
DisProt Annotation
TM Helix Prediction
No TM helices