Primary Information |
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BoMiProt ID | Bomi10043 |
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Protein Name | Trichohyalin-like protein 1 |
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Organism | Bos taurus |
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Uniprot ID | A6QP92 |
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Milk Fraction | Whey |
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Ref Sequence ID | NP_001193524.1 |
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Aminoacid Length | 872 |
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Molecular Weight | 95773 |
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FASTA Sequence |
Download |
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Gene Name | TCHHL1 |
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Gene ID | 518825 |
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Protein Existence Status | reviewed |
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Secondary Information |
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Protein Function | expressed in the basal layer of the normal epidermis.associated with the proliferation and antiapotosis of keratinocytes. |
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Biochemical Properties | TCHHL1 contains an EF-hand domain in the N-terminus, one trans-membrane domain and a nuclear localization signal. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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Predicted Disorder Regions | 83-115, 140-217, 252-461, 508-621, 665-839, 860-872 |
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DisProt Annotation | |
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TM Helix Prediction | No TM helices |
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Bibliography | Yamakoshi T, Makino T, Ur Rehman M, Yoshihisa Y, Sugimori M, Shimizu T. Trichohyalin-like 1 protein, a member of fused S100 proteins, is expressed in normal and pathologic human skin. Biochem Biophys Res Commun. 2013 Mar 1;432(1):66-72. doi: 10.1016/j.bbrc.2013.01.084. Epub 2013 Jan 29. PMID: 23376073. |