Primary Information |
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| BoMiProt ID | Bomi10001 |
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| Protein Name | Transmembrane protein 180/Major facilitator superfamily domain-containing 13A |
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| Organism | Bos taurus |
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| Uniprot ID | Q58CT4 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001014925.1 |
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| Aminoacid Length | 517 |
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| Molecular Weight | 57198 |
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| FASTA Sequence |
Download |
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| Gene Name | MFSD13A/TMEM180 |
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| Gene ID | 514370 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | may play an important role in the uptake or metabolism of glutamine and arginine in cancer cell.cation symporter. |
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| Biochemical Properties | 12-transmembrane protein. Both the N-terminus and C-terminus of TMEM180 are extracellularly exposed. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | 442-458, 501-509 |
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| DisProt Annotation | |
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| TM Helix Prediction | 9 TMHs; (15-37), (101-119), (123-141), (162-184), (196-214), (266-288), (303-325), (332-354), (468-490) |
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| Bibliography | Anzai T, Matsumura Y. Topological analysis of TMEM180, a newly identified membrane protein that is highly expressed in colorectal cancer cells. Biochem Biophys Res Commun. 2019 Dec 10;520(3):566-572. doi: 10.1016/j.bbrc.2019.10.070. Epub 2019 Oct 12. PMID: 31615651. |
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