Browse BoMiProt


Database of Inflammation Markers

UniProt ID Protein Name Function in Subclinical Mastitis Trend of expression Reference
P07589 Fibronectin ECM remodeling; increases with tissue damage. CM>SCM>H View
Q9MYV8 Haptoglobin Acute-phase protein; rises with inflammation & neutrophil influx. CM>SCM>H View
Q0VCX2 78 kDa GRP78 ER stress marker; elevated during infection stress. CM<SCM<H View
B0JYQ0 ALB protein Leakage marker due to barrier disruption. CM<SCM<H View
B0JYN6 Alpha-2-HS-glycoprotein Negative acute-phase protein; decreases in mastitis. CM<SCM<H View
Q3MHN2 Complement C9 Part of MAC; enhances bacterial killing. CM<SCM<H View
P15396 ENPP3 Immune-modulating enzyme; increases with epithelial stress. CM<SCM<H View
P80195 GLYCAM1 Mammary adhesion molecule; decreases during gland inflammation. CM<SCM<H View
Q3SZV7 Hemopexin Binds free heme; increases during oxidative stress. CM<SCM<H View
P40673 HMGB2 Alarmin released during cell damage; stimulates inflammation. CM<SCM<H View
A4IFI0 IGLL1 protein Reflects humoral immune activation. CM<SCM<H View
F1MMP5 ITIH1 ECM stabilizer; increases with tissue remodeling. CM<SCM<H View
Q0QEQ4 Isocitrate dehydrogenase 1 fragment Marker of metabolic stress in infected glands. CM<SCM<H View
A5D7R6 ITIH2 Acute-phase protein; stabilizes inflamed tissue matrix. CM<SCM<H View
Q705V4 Kappa-casein fragment Protein breakdown; indicates proteolysis during mastitis. CM<SCM<H View
Q5E9B1 LDHB Elevated during neutrophil influx and hypoxia. CM<SCM<H View
A7E340 Mucin 15 Barrier component; altered with epithelial damage. CM<SCM<H View
Q29437 Amine oxidase (liver) Generates H?O?; linked to oxidative stress. CM<SCM<H View
O46406 Amine oxidase (lung) Similar role in oxidative metabolism during infection. CM<SCM<H View
Q2HJB6 Procollagen C-endopeptidase enhancer Tissue remodeling during chronic inflammation. CM<SCM<H View
Q2KIT0 Protein HP-20 homolog Milk metabolic protein; decreases with inflammation. CM<SCM<H View
Q2KIX7 Protein HP-25 homolog 1 Reduced during mammary inflammation. CM<SCM<H View
Q9TTE1 Serpin A3-1 Inhibits neutrophil proteases; elevated in mastitis. CM<SCM<H View
P80457 Xanthine dehydrogenase/oxidase Generates ROS; increases oxidative activity. CM<SCM<H View
E1B8L8 Fc receptor IgA/IgM Supports antibody-mediated pathogen clearance. CM<SCM<H View
B9TUB7 Cathelicidin 2 Antimicrobial peptide; upregulated in mastitis. SCM>CM>H View
F1N3A1 Thrombospondin-1 Regulates inflammation & ECM remodeling. SCM>CM>H View
B9UKM3 Cathelicidin 6 Antimicrobial peptide; innate immune activation. SCM>CM>H View
P19661 Cathelicidin 3 Antimicrobial; increases against pathogens. SCM>CM>H View
P33046 Cathelicidin 4 Strong antimicrobial peptide in mastitis. SCM>CM>H View
G8JL06 Histone H2B NET formation marker from neutrophils. SCM>CM>H View
Q2M2T1 Histone H2B type 1-K NET-associated immune defense. SCM>CM>H View
A6QLB7 Adenylyl cyclase?associated protein Cytoskeletal remodeling during inflammation. H=CM< SCM View
P10152 Angiogenin-1 Host-defense RNase; antimicrobial. H=CM< SCM View
B0JYL8 Cofilin 1 Actin dynamics; reflects cell stress. H=CM< SCM View
P02702 Folate receptor ? Altered epithelial turnover in mastitis. H=CM< SCM View
F1MNQ4 SOD1 Neutralizes ROS; antioxidant response. H=CM< SCM View
Q2KIS7 Tetranectin ECM remodeling and immune regulation. H=CM< SCM View
P26779 Prosaposin Immune-modulatory and lipid metabolism changes. H=CM< SCM View
B1H0W7 PGD2 synthase Produces inflammatory prostaglandins. H=CM< SCM View
P60712 Actin cytoplasmic 1 Cell damage & neutrophil influx marker. H>SCM=CM View
Q0IIH5 Nucleobindin 2 Immune signaling in inflammation. H>SCM=CM View
Q0P569 Nucleobindin 1 Stress and immune pathway modulation. H>SCM=CM View
Q32KV6 SIL1 ER stress in milk-synthesizing cells. H>SCM=CM View
Q58DM6 Osteopontin Strong pro-inflammatory cytokine-like protein. H>SCM=CM View
P63258 Actin cytoplasmic 2 Leakage marker; cell disruption. H>SCM=CM View
P41361 Antithrombin III Anti-inflammatory anticoagulant response. H>SCM=CM View
Q32PJ1 ABCG2 Altered secretion transport in mastitis. H>SCM=CM View
Q864S5 PPIase Protein-folding enzyme; elevated during stress. H>SCM=CM View
Q95121 PEDF Anti-inflammatory modulator. H>SCM=CM View
P26201 Platelet glycoprotein 4 Immune cell transport and adhesion. H>SCM=CM View
P00735 Prothrombin Coagulation increase due to tissue injury. H>SCM=CM View
Q0IIG8 Rab-18 Vesicle trafficking during immune activation. H>SCM=CM View
Q862P9 ?-actin fragment Breakdown marker reflecting tissue damage. H>SCM=CM View
I1VE25 ?-casein fragment Enhanced proteolysis in mastitic milk. H>SCM=CM View
Q32T06 Endopin 2 Serpin-like activity; may regulate proteases. H>SCM=CM View
P08037-2 ?1,4-Galactosyltransferase 1 (short) Altered milk glycosylation in inflammation. H>SCM=CM View
P30932 CD9 antigen Leukocyte/exosome activation marker. H=SCM< CM View
G8JKX6 Tetraspanin Immune cell communication. H=SCM< CM View
Q3SZH5 Angiotensinogen Precursor of inflammatory peptides. H<SCM=CM View
P02070 Hemoglobin ? Leakage due to barrier breakdown. H<SCM=CM View
P25326 Cathepsin S Immune protease; elevated in mastitis. H<SCM=CM View
G3N053 Histone H2B Neutrophil extracellular trap component. H<SCM=CM View
Q32L48 H2B type 1-N NET-driven pathogen defense. H<SCM=CM View
F1MIH9 Phospholipase B-like Lipid remodeling during inflammation. H<SCM=CM View
Q2KIY5 Phospholipase B-like 2 Similar lipid metabolism role. H<SCM=CM View
Q6RUS2 Butyrophilin fragment MFGM structural changes during inflammation. H>SCM=CM View
Q3ZBD7 Glucose-6-phosphate isomerase Increased metabolic activity. H>SCM=CM View
A1L528 RAB1A Regulates secretory pathways in inflamed cells. H>SCM=CM View
P50397 Rab GDI-? Controls vesicle trafficking in immune response. H>SCM>CM View
A6H6X2 ANG2 protein Immune-modulatory secreted protein. H=CM<SCM View
Q6KDN5 Complement C3 fragment Key innate immune activation protein. H=CM<SCM View
Q5DPW9 Cystatin Inhibits cathepsins; regulates proteolysis. H=CM<SCM View
Q3ZCL0 CRISP2 Secreted protein altered during inflammation. H=CM<SCM View
Q4VS17 FGFBP fragment Tissue repair?associated protein. H=CM<SCM View
Q9MZ06 FGFBP1 Growth factor binding; promotes repair. H=CM<SCM View
G3MWV5 Histone H1 family member e NET-associated immune defense. H=CM<SCM View
P02253 Histone H1.2 Released during neutrophil activation. H=CM<SCM View
E1BI67 IL-18 binding protein Anti-inflammatory decoy receptor. H=CM<SCM View
P15467 Ribonuclease 4 Antimicrobial RNase. H=CM<SCM View
F1MN78 Serpin B4 Protease inhibitor; controls inflammation. H=CM<SCM View