Search by BoMiProt ID - Bomi2599


Primary Information

BoMiProt ID Bomi2599
Protein Name Dehydrogenase/reductase (SDR family) member 1
Organism Bos taurus
Uniprot IdQ2KIS4
Milk FractionMFGM, Exosome
Ref Sequence Id NP_001039759.1
Amino Acid Lenth 312
Molecular Weight 34020
Fasta Sequence https://www.uniprot.org/uniprot/Q2KIS4.fasta
Gene Name DHRS1
Gene Id 528832
Protein Existence Status Unreveiwed:Experimental evidence at transcript level

Secondry Information

Protein Function member of the short-chain dehydrogenase/reductase (SDR) superfamily; play an important role in various (patho)biochemical pathways including intermediary metabolism and biotransformation of xenobiotics
Biochemical Properties integral protein of the endoplasmic reticulum, facing towards the lumen with a reducing activity toward several substrates bearing carbonyl groups, such as steroid hormones, xenobiotics and model substrates prerferably NADPH as the cofactor; mostly three transmembrane segments; hydrophobic middle and C-term predicted transmembrane segments might be part of the homodimer formation/ interaction sites
Significance in milk oxidoreductase enzyme in milk
PTMs No glycosylation motif
Linking IDs Bomi55
Bibliography 1. Hirokawa, T., Boon-Chieng, S., & Mitaku, S. (1998). SOSUI: classification and secondary structure prediction system for membrane proteins. Bioinformatics (Oxford, England), 14(4), 378–379. https://doi.org/10.1093/bioinformatics/14.4.378.
2. Stambergova, H., Skarydova, L., Dunford, J. E., & Wsol, V. (2014). Biochemical properties of human dehydrogenase/reductase (SDR family) member 7. Chemico-Biological Interactions, 207, 52–57. https://doi.org/10.1016/j.cbi.2013.11.003.