Search by BoMiProt ID - Bomi9999


Primary Information

BoMiProt ID Bomi9999
Protein Name Transmembrane protein 158/Ras-induced senescence protein 1
Organism Bos taurus
Uniprot Id A2VDX9
Milk FractionWhey,Exosome,MFGM
Ref Sequence Id NP_001075095.1
Aminoacid Length 291
Molecular Weight 29638
Fasta Sequence https://www.uniprot.org/uniprot/A2VDX9.fasta
Gene Name TMEM158
Gene Id 788085
Protein Existence Status reviewed

Secondary Information

Protein Function Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. Receptor for brain injury-derived neurotrophic peptide (BINP)
PTMs N linked glycosylation on Asn
Predicted Disorder Regions 3 disordered segments; (37-70), (155-167), (286-291)
DisProt Annotation
TM Helix Prediction 2TMHs ;(220-242) & (262-284)
Bibliography  "Entrez Gene: TMEM158 transmembrane protein 158