Primary Information |
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BoMiProt ID | Bomi9999 |
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Protein Name | Transmembrane protein 158/Ras-induced senescence protein 1 |
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Organism | Bos taurus |
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Uniprot ID | A2VDX9 |
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Milk Fraction | Whey,Exosome,MFGM |
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Ref Sequence ID | NP_001075095.1 |
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Aminoacid Length | 291 |
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Molecular Weight | 29638 |
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FASTA Sequence |
Download |
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Gene Name | TMEM158 |
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Gene ID | 788085 |
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Protein Existence Status | reviewed |
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Secondary Information |
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Protein Function | Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. Receptor for brain injury-derived neurotrophic peptide (BINP) |
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PTMs | N linked glycosylation on Asn |
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Predicted Disorder Regions | 3 disordered segments; (37-70), (155-167), (286-291) |
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DisProt Annotation | |
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TM Helix Prediction | 2TMHs ;(220-242) & (262-284) |
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Bibliography | "Entrez Gene: TMEM158 transmembrane protein 158 |