Search by BoMiProt ID - Bomi9841


Primary Information

BoMiProt ID Bomi9841
Protein Name Thyroxine 5-deiodinase/5DIII DIOIII/Type 3 DI/Type III iodothyronine deiodinase
Organism Bos taurus
Uniprot IdQ5I3B1
Milk Fractionwhey
Ref Sequence Id NP_001010993.2
Aminoacid Length 301
Molecular Weight 33888
Fasta Sequence https://www.uniprot.org/uniprot/Q5I3B1.fasta
Gene Name DIO3
Gene Id 494549
Protein Existence Status Reviewed

Secondary Information

Presence in other biological fluids/tissue/cells Highly expressed in mammary gland
Protein Function It is responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine)
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction 1TMH; (42-64)
Bibliography Yang, W., Li, D., Wang, G., Wu, X., Zhang, M., Zhang, C., Cui, Y., & Li, S. (2017). Expression and imprinting of DIO3 and DIO3OS genes in Holstein cattle. Journal of genetics, 96(2), 333–339. https://doi.org/10.1007/s12041-017-0780-0