Search by BoMiProt ID - Bomi9810


Primary Information

BoMiProt ID Bomi9810
Protein Name Thioredoxin, mitochondrial/MTRX/Mt-Trx/Thioredoxin-2
Organism Bos taurus
Uniprot IdQ95108
Milk FractionWhey
Ref Sequence Id NP_776633.1
Aminoacid Length 166
Molecular Weight 18416
Fasta Sequence https://www.uniprot.org/uniprot/Q95108.fasta
Gene Name TXN2
Gene Id 281557
Protein Existence Status reviewed

Secondary Information

Protein Function antioxidant system in defense against oxidative stress through its disulfide reductase activity regulating protein dithiol/disulfide balance. 
PTMs Acetylation,Disulfide bond
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Significance of PTMs cysteine 73, glutathionylated cysteines in plant thioredoxin are located in the flexible α3– β4 loop.Both in mammals and plants,Glutathionylation of thioredoxin led to a reduction in the enzymatic activity of thioredoxin under conditions of oxidative stress.