Search by BoMiProt ID - Bomi9603


Primary Information

BoMiProt ID Bomi9603
Protein Name Suprabasin
Organism Bos taurus
Uniprot IdA6QQF6
Milk Fractionwhey
Ref Sequence Id NP_001098467.1
Aminoacid Length 557
Molecular Weight 56854
Fasta Sequence https://www.uniprot.org/uniprot/A6QQF6.fasta
Gene Name SBSN
Gene Id 540452
Protein Existence Status Reviewed

Secondary Information

Protein Function plays a role in the process of epidermal differentiation.SBSN may play a role in human tumourigenesis.
Biochemical Properties Three SBSN isoforms code for the secreted proteins with putative function as signalling molecules.The open reading frame codes for a small protein rich in glycine, with short tandem repeats in the central region.
PTMs Phosphorylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions 25-372, 399-408, 423-453, 464-529
DisProt Annotation
TM Helix Prediction No TM helices
Significance of PTMs protein kinase C phosphorylation sites are present in COOH.Also revealed 2 casein kinase II phosphorylation sites and 73 potentialN-myristoylation sites.
Bibliography 1.Park GT, Lim SE, Jang SI, Morasso MI. Suprabasin, a novel epidermal differentiation marker and potential cornified envelope precursor. J Biol Chem. 2002 Nov 22;277(47):45195-202. doi: 10.1074/jbc.M205380200. Epub 2002 Sep 12. PMID: 12228223; PMCID: PMC1283087. 2.Pribyl, M., Hodny, Z., & Kubikova, I. (2021). Suprabasin-A Review. Genes, 12(1), 108. https://doi.org/10.3390/genes12010108