Search by BoMiProt ID - Bomi9597


Primary Information

BoMiProt ID Bomi9597
Protein Name Suppressor of tumorigenicity 7 protein-like
Organism Bos taurus
Uniprot IdA3KN28
Milk FractionWhey
Ref Sequence Id NP_001076950.1
Aminoacid Length 555
Molecular Weight 62636
Fasta Sequence https://www.uniprot.org/uniprot/A3KN28.fasta
Gene Name ST7L
Gene Id 534657
Protein Existence Status reviewed

Secondary Information

Protein Function Tumour supressor protein.found to decrease glycogen synthase kinase (GSK)-3β phosphorylation and downregulate active β-catenin protein expression, thereby leading to repression of β-catenin transcriptional activity.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions 9-15, 126-147, 272-280
DisProt Annotation
TM Helix Prediction 2TMHs; (38-60) and (80-102)
Bibliography Wang H, Sun L, Jiang J, Yu S, Zhou Q. Suppression of the proliferation and invasion of breast cancer cells by ST7L occurs through inhibition of activation of Wnt/GSK-3β/β-catenin signalling. Clin Exp Pharmacol Physiol. 2020 Jan;47(1):119-126. doi: 10.1111/1440-1681.13166. Epub 2019 Sep 9. PMID: 31429477.