Primary Information |
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| BoMiProt ID | Bomi9369 |
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| Protein Name | Solute carrier family 43 member 3 |
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| Organism | Bos taurus |
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| Uniprot Id | Q1JPD8 |
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| Milk Fraction | Whey |
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| Ref Sequence Id | NP_001033215.1 |
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| Aminoacid Length | 489 |
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| Molecular Weight | 54424 |
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| Fasta Sequence | https://www.uniprot.org/uniprot/Q1JPD8.fasta |
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| Gene Name | SLC43A3 |
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| Gene Id | 516840 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Involved in the transport endogenous nucleobases,identified as a purine-selective nucleobase transporter. |
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| PTMs | Phosphorylation at Ser/Thr, Glycosylation at Asn |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q1JPD8|S43A3_BOVIN Equilibrative nucleobase transporter 1 OS=Bos taurus OX=9913 GN=SLC43A3 PE=2 SV=1
MQGRSLPFRVATLVTGLLECLGFAGVLFGWTSLVFVFKKQHYFEELCELDAGSLGN*56ATGL
DECRARDERFSLIFTLASFTINFMTFPTGYIFDRFKTTVARLIAIFLYTSATLTIAFTSA
DSAVLLFLAMPMLAVGGILFLITNLQIGNLFGKHRSTIITMYNGAFDSSSAVFLIIKLLY
EQGVTIKASFLFISVCSAWHVGRTLLLMPRGHIPYPLPANYHYGLCSRDSPPEEDKKEAE
SEKLELQSKEFLS*253PKKET*258PGQQQAPGSFWSHTFSPRFAWHVVWLSVIQLWHYLFIGTLNS
LLNNLASRDSAIVSTYTNAFAVTQFFGVLCAPWNGLLMDRLKHKYQEEAKRTGAVAKAAA
LRSVVPSLTLTSLLSLGFAVCASIPVLPLQYATFILQVVSRSFLYGCNAAFLTLAFPSEH
FGKLFGLVMALSAVVSLLQFPLFTLIKGPLQNDPLYVNLMLVLLTLLTFIHPFLVNRECQ
RKESPREVA |
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | 12TMHs ; (13-35), (70-92), (99-117), (123-145), (158-180), (184-202), (278-296), (315-337), (358-380), (395-417), (424-446), (455-473) |
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| Bibliography | 1.Takenaka R, Yasujima T, Furukawa J, Hishikawa Y, Yamashiro T, Ohta K, Inoue K, Yuasa H. Functional Analysis of the Role of Equilibrative Nucleobase Transporter 1 (ENBT1/SLC43A3) in Adenine Transport in HepG2 Cells. J Pharm Sci. 2020 Aug;109(8):2622-2628. doi: 10.1016/j.xphs.2020.04.013. Epub 2020 Apr 25. PMID: 32339528. 2. |
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