Search by BoMiProt ID - Bomi9251


Primary Information

BoMiProt ID Bomi9251
Protein Name S-methyl-5'-thioadenosine phosphorylase/5'-methylthioadenosine phosphorylase
Organism Bos taurus
Uniprot IdQ3MHF7
Milk FractionExosomes,MFGM
Ref Sequence Id XP_002689552.1
Aminoacid Length 283
Molecular Weight 31256
Fasta Sequence https://www.uniprot.org/uniprot/Q3MHF7.fasta
Gene Name MTAP
Gene Id 782907
Protein Existence Status Reviewed

Secondary Information

Protein Function It catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Also involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.
PTMs N6-acetylation at Lysine
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.Della Ragione F, Oliva A, Gragnaniello V, Russo GL, Palumbo R, Zappia V. Physicochemical and immunological studies on mammalian 5'-deoxy-5'-methylthioadenosine phosphorylase. J Biol Chem. 1990 Apr 15;265(11):6241-6. PMID: 2108157.