Primary Information |
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| BoMiProt ID | Bomi9069 |
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| Protein Name | Serine-threonine kinase receptor-associated protein |
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| Organism | Bos taurus |
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| Uniprot ID | Q5E959 |
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| Milk Fraction | Exosomes |
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| Ref Sequence ID | NP_001015567.1 |
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| Aminoacid Length | 350 |
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| Molecular Weight | 38485 |
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| FASTA Sequence |
Download |
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| Gene Name | STRAP |
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| Gene ID | 510201 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Presence in other biological fluids/tissue/cells | vertebral column |
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| Protein Function | The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. STRAP plays a role in the cellular distribution of the SMN complex. |
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| PTMs | Phosphorylation at Ser/Tyr |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q5E959|STRAP_BOVIN Serine-threonine kinase receptor-associated protein OS=Bos taurus OX=9913 GN=STRAP PE=2 SV=1
MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKG
AVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQ
DKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSL
NFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFVVA
GGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTY
GLWKCVLPEEDS*312GELAKPKINFPETAEEELEEIAS*335ENS*338DSIY*342SSTPEVKA |
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| Predicted Disorder Regions | 311-350 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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