Primary Information |
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BoMiProt ID | Bomi9030 |
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Protein Name | Serine incorporator 2/Tumor differentially expressed protein 2-like |
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Organism | Bos taurus |
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Uniprot ID | Q58CW5 |
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Milk Fraction | Exosomes |
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Aminoacid Length | 452 |
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Molecular Weight | 50425 |
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FASTA Sequence |
Download |
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Gene Name | SERINC2 |
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Protein Existence Status | Reviewed |
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Secondary Information |
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Protein Function | SERINC2 is a transmembrane protein that belongs to the SERINC family, and it functions to transform serine into lipid membranes during synthesis.SERINC plays essential roles in regulating the biosynthesis of multiple membrane lipids, such as phosphatidylserine and sphingolipid molecules. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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Predicted Disorder Regions | NA |
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DisProt Annotation | |
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TM Helix Prediction | 10TMHs; (40-58),(96-118),(131-149),(158-180),(201-223),(238-256),(268-286),(321-339),(382-404),(419-441) |
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Bibliography | 1.Qi C, Lei L, Hu J, Wang G, Liu J, Ou S. Serine Incorporator 2 (SERINC2) Expression Predicts an Unfavorable Prognosis of Low-Grade Glioma (LGG): Evidence from Bioinformatics Analysis. J Mol Neurosci. 2020 Oct;70(10):1521-1532. doi: 10.1007/s12031-020-01620-w. Epub 2020 Jul 8. PMID: 32642801; PMCID: PMC7497444. 2.Ren W-H, Yang C-Y, Yang X-M, Yu L. siRNA-mediated knockdown of hTDE2 retards cell cycle progression through transcriptional activation of p21. Oncol Rep. 2014;31(3):1314–1322. doi: 10.3892/or.2014.2980. |