Search by BoMiProt ID - Bomi9030


Primary Information

BoMiProt ID Bomi9030
Protein Name Serine incorporator 2/Tumor differentially expressed protein 2-like
Organism Bos taurus
Uniprot IDQ58CW5
Milk FractionExosomes
Aminoacid Length 452
Molecular Weight 50425
FASTA Sequence Download
Gene Name SERINC2
Protein Existence Status Reviewed

Secondary Information

Protein Function SERINC2 is a transmembrane protein that belongs to the SERINC family, and it functions to transform serine into lipid membranes during synthesis.SERINC plays essential roles in regulating the biosynthesis of multiple membrane lipids, such as phosphatidylserine and sphingolipid molecules.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction 10TMHs; (40-58),(96-118),(131-149),(158-180),(201-223),(238-256),(268-286),(321-339),(382-404),(419-441)
Bibliography 1.Qi C, Lei L, Hu J, Wang G, Liu J, Ou S. Serine Incorporator 2 (SERINC2) Expression Predicts an Unfavorable Prognosis of Low-Grade Glioma (LGG): Evidence from Bioinformatics Analysis. J Mol Neurosci. 2020 Oct;70(10):1521-1532. doi: 10.1007/s12031-020-01620-w. Epub 2020 Jul 8. PMID: 32642801; PMCID: PMC7497444. 2.Ren W-H, Yang C-Y, Yang X-M, Yu L. siRNA-mediated knockdown of hTDE2 retards cell cycle progression through transcriptional activation of p21. Oncol Rep. 2014;31(3):1314–1322. doi: 10.3892/or.2014.2980.