Search by BoMiProt ID - Bomi8742


Primary Information

BoMiProt ID Bomi8742
Protein Name Retrotransposon-like protein 1/Paternally expressed gene 11 protein homolog/Retrotransposon-derived protein PEG11
Organism Bos taurus
Uniprot IdQ52QI2
Milk FractionWhey
Ref Sequence Id NP_001181949.1
Aminoacid Length 1331
Molecular Weight 151448
Fasta Sequence https://www.uniprot.org/uniprot/Q52QI2.fasta
Gene Name RTL1/PEG11
Gene Id 606737
Protein Existence Status reviewed

Secondary Information

Protein Function  is expressed as a full-length protein in skeletal muscle from Callipyge sheep.
Biochemical Properties  The region of PEG11 corresponding with that encoding antisense mir-431 is associated with propensity for coiled coil formation. Whilst coiled coils are a general feature of the PEG11 protein sequence, the region corresponding to that encoded by antisense mir-431 is highly conserved in its propensity for coiled coil formation suggesting an important function possibly involving protein-protein interactions.
PTMs Lipolyation, Myristoylation, Phosphorylation at Ser
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions 1-140, 560-600, 998-1028, 1324-1327
DisProt Annotation
TM Helix Prediction No TM helices
Additional Comments Ectopic Expression of Retrotransposon-Derived PEG11/RTL1 Contributes to the Callipyge Muscular Hypertrophy
Bibliography 1.Xu X, Ectors F, Davis EE, Pirottin D, Cheng H, Farnir F, Hadfield T, Cockett N, Charlier C, Georges M, Takeda H. Ectopic Expression of Retrotransposon-Derived PEG11/RTL1 Contributes to the Callipyge Muscular Hypertrophy. PLoS One. 2015 Oct 16;10(10):e0140594. doi: 10.1371/journal.pone.0140594. PMID: 26474044; PMCID: PMC4608697. 2.Byrne K, Colgrave ML, Vuocolo T, Pearson R, Bidwell CA, Cockett NE, Lynn DJ, Fleming-Waddell JN, Tellam RL. The imprinted retrotransposon-like gene PEG11 (RTL1) is expressed as a full-length protein in skeletal muscle from Callipyge sheep. PLoS One. 2010 Jan 8;5(1):e8638. doi: 10.1371/journal.pone.0008638. PMID: 20072617; PMCID: PMC2799525.