Primary Information |
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| BoMiProt ID | Bomi8707 |
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| Protein Name | Replication initiator 1 |
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| Organism | Bos taurus |
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| Uniprot ID | Q0VCC5 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001068989.1 |
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| Aminoacid Length | 559 |
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| Molecular Weight | 62372 |
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| FASTA Sequence |
Download |
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| Gene Name | REPIN1 |
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| Gene ID | 511510 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Participare in initiation of DNA replication.REPIN1 appears to be involved in the regulation of cell size and glucose transport in adipocytes |
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| Biochemical Properties | Acts as TF, binds to the DNA consensus sequence 5-prime-CAGCTG-3-prime.567-amino acid long.contains 15 C2H2 zinc finger DNA-binding motifs which are organized into 3 clusters.A proline-rich region is located between ZF8 and ZF9. |
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| PTMs | Acetylation, Phosphorylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q0VCC5|REPI1_BOVIN Replication initiator 1 OS=Bos taurus OX=9913 GN=REPIN1 PE=2 SV=1
MLERRCRGPVAMGPAQPRLLSGPSQES*27PQT*30LEKEPQGLRSRGTAAAQSGGQALGRAHRCA
HCRRHFPGWVALWLHARRCQARLPRPCPECGRRFRHAPFLALHCQVHAAATPDQGFACHL
CGQSFRGWVALVLHLRAHSAAKRPIACPACERRFWRRKQLRAHSRRCHPPAPEARPFICG
NCGRSFAQWDQLVTHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCAC
CGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCTECGRR
FRHKPNLLSHSKIHKRSEGSAQGGPQPPASAPERTPEPPPEPAPEPAEVPVGPGQPSAAA
EAPPSLHTCADCGRGFRLERFLRAHQRQHGGERPFACAECGKHFGKKTHLVAHSRVHSGE
RPFACEECGRRFSQGSHLAAHRRDHAPERPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYV
CPECGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAIC
GQTFDDEGKLLAHQKKHDV
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | 1.Ruschke K, Illes M, Kern M, Klöting I, Fasshauer M, Schön MR, Kosacka J, Fitzl G, Kovacs P, Stumvoll M, Blüher M, Klöting N. Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes. Biochem Biophys Res Commun. 2010 Sep 17;400(2):246-51. doi: 10.1016/j.bbrc.2010.08.049. Epub 2010 Aug 19. PMID: 20727851. |
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