Search by BoMiProt ID - Bomi8605


Primary Information

BoMiProt ID Bomi8605
Protein Name Ragulator complex protein LAMTOR1/Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1
Organism Bos taurus
Uniprot IdQ3T0D8
Milk FractionWhey
Ref Sequence Id NP_001029941.1
Aminoacid Length 161
Molecular Weight 17731
Fasta Sequence https://www.uniprot.org/uniprot/Q3T0D8.fasta
Gene Name LAMTOR1
Gene Id 614849
Protein Existence Status Reviewed

Secondary Information

Presence in other biological fluids/tissue/cells pons
Protein Function It acts as a part of the ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag.
PTMs Myristoylation, Phosphorylation at Ser
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
>sp|Q3T0D8|LTOR1_BOVIN Ragulator complex protein LAMTOR1 OS=Bos taurus OX=9913 GN=LAMTOR1 PE=2 SV=1 MGCCYSSENEDSDQDREERKLLLDPSS*27PPTKALNGAEPNYHS*42LPSARTDEQALLSS*56ILAK TASNIIDVSAADSQGMEQHEYMDRARQYSTRLAVLSSS*98LTHWKKLPPLPSLTSQPHQVLA SEPVPFSDLQQVSRIAAYAYS*141ALSQIRVDAKEELVVQFGIP
Predicted Disorder Regions 1-52, 71-87, 107-124
DisProt Annotation
TM Helix Prediction No TM helices