Primary Information
BoMiProt ID	Bomi8407
Protein Name	Protein PROCA1
Organism	Bos taurus
Uniprot ID	A7E371
Milk Fraction	whey
Ref Sequence ID	NP_001160040.1
Aminoacid Length	376
Molecular Weight	42242
FASTA Sequence	Download
Gene Name	PROCA1
Gene ID	510175
Protein Existence Status	Reviewed
Secondary Information
Protein Function	It displays phospholipase A2 activity
Biochemical Properties	It interacts with cyclin A1.The deduced protein has an N-terminal proline-rich region and was predicted to localize to the nucleus. It also has 2 possible phosphorylation sites. Real-time RT-PCR of 16 human tissues detected high PROCA1 expression in testis, with little to no expression in other tissues.
PTMs	Phosphorylation on Ser
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|A7E371|PRCA1_BOVIN Protein PROCA1 OS=Bos taurus OX=9913 GN=PROCA1 PE=2 SV=2 MWVRTTLRIERWTKEKTEDDTSSWDESSTDINRLPSWGRGHLLASVESSTDASTLSSEGE FKNTDRCCWKHKCAGHIVRPFSPDCVHHDVHLHSLSHCDCDSRLKDCSEKTNSSSGDVGP TCSRDVDSTCFDIIQSPCFELIPEEECVERFWYGWCKSYRPVSVAVIHHPIHHECGADDL NQEEEEEEEEESKPPIPTQVGPTPTDSPTDTGMSMITGAPDSAAPITIWRSESPTGKSQG NRVIKKIKKKKEKDKEEETDEKEKAKVKKKVKKGKLMKKKSPVKSESPPDLSRSLSPREL ARMSESSPDSRQDLESEDS*319YNDPGREEPS*329S*330EDIVESSSPRKREKNGVQVKKPGLKTSPVK KINKRRS*367PPASNPNLS*376
Predicted Disorder Regions	16-29, 45-57, 114-120, 174-376
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	1.Diederichs, S., Baumer, N., Ji, P., Metzelder, S. K., Idos, G. E., Cauvet, T., Wang, W., Moller, M., Pierschalski, S., Gromoll, J., Schrader, M. G., Koeffler, H. P., Berdel, W. E., Serve, H., Muller-Tidow, C. Identification of interaction partners and substrates of the cyclin A1-CDK2 complex. J. Biol. Chem. 279: 33727-33741, 2004. 2.Bovine Genome Sequencing and Analysis Consortium, Elsik, C. G., Tellam, R. L., Worley, K. C., Gibbs, R. A., Muzny, D. M., Weinstock, G. M., Adelson, D. L., Eichler, E. E., Elnitski, L., Guigó, R., Hamernik, D. L., Kappes, S. M., Lewin, H. A., Lynn, D. J., Nicholas, F. W., Reymond, A., Rijnkels, M., Skow, L. C., Zdobnov, E. M., … Zhao, F. Q. (2009). The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science (New York, N.Y.), 324(5926), 522–528. https://doi.org/10.1126/science.1169588