Primary Information |
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| BoMiProt ID | Bomi8362 |
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| Protein Name | Protein LRATD1/LRAT domain-containing 1/Protein FAM84A |
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| Organism | Bos taurus |
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| Uniprot Id | Q3ZCA1 |
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| Milk Fraction | Whey |
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| Ref Sequence Id | NP_001029831.1 |
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| Aminoacid Length | 297 |
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| Molecular Weight | 33127 |
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| Fasta Sequence | https://www.uniprot.org/uniprot/Q3ZCA1.fasta |
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| Gene Name | LRATD1/FAM84A |
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| Gene Id | 539071 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | FAM84A expression increased cell motility in NIH3T3 cells, and that phosphorylation of serine 38 of FAM84A was associated with morphology of cells. |
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| PTMs | Phosphorylation at Ser |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q3ZCA1|LRAT1_BOVIN Protein LRATD1 OS=Bos taurus OX=9913 GN=LRATD1 PE=2 SV=1
MGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFS*38DEEEDLDERGQPDKFGVKAPPG
CAPCPESPSRHHHHHHHHHLLHQLVLNETQFSAFRGQECIFSKVSGGPQGADLSVYAVTA
LPALCEPGDLLELLWLQPAPEPPAPAPHWAVYVGGGQIIHLCQGEIRQDSLYEAGAANVG
RVVNSWYRYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFGKREFKAGGEVPAG
TQPPQQQYYLKVHLADNKVHTARFHSLEDLIREKRRIDASGRLRVLQELADLVDDKE
|
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| Predicted Disorder Regions | 1-27, 39-76, 233-244 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Additional Comments | Up-regulation of FAM84A plays a critical role in progression of colon cancer. |
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| Bibliography | Kobayashi T, Masaki T, Sugiyama M, Atomi Y, Furukawa Y, Nakamura Y. A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells. Int J Oncol. 2006 Aug;29(2):341-7. PMID: 16820875. |
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