Primary Information |
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| BoMiProt ID | Bomi8337 |
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| Protein Name | Protein FAM89A |
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| Organism | Bos taurus |
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| Uniprot ID | A6QQF7 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001094727.1 |
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| Aminoacid Length | 178 |
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| Molecular Weight | 18888 |
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| FASTA Sequence |
Download |
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| Gene Name | FAM89A |
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| Gene ID | 616421 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | immune responses pathways and various pathologies such as atherosclerosis and glioma cell expression. |
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| Biochemical Properties | molecular mass of 18.6kDa and a predicted isoelectric point of 5.64. 184 amino acids in length.Composition of FAM89A protein is notable for its abundance of four amino acids; Leucine (14.1%), Glycine (12.0%), Alanine (11.4%) and Serine (11.4%). FAM89A shows five periodic repeats of leucine residues at every seventh amino acid position at positions 81-115, which is characteristic of its predicted leucine zipper structural motif.conserved leucine-rich adapter protein domain (LURAP) called PF14854 located at amino acid positions 84-122.FAM89A is predicted to be 40% alpha helix, 11% extended strand, and 49% random coils. |
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| PTMs | Phosphorylation/O-Linked β-N-acetylglucosamine,Glycation,SUMOylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | 4 disordered segments; (1-11), (23-41), (55-75), (121-171) |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | Gómez-Carballa A, Cebey-López M, Pardo-Seco J, Barral-Arca R, Rivero-Calle I, Pischedda S, Currás-Tuala MJ, Gómez-Rial J, Barros F, Martinón-Torres F, Salas A. A qPCR expression assay of IFI44L gene differentiates viral from bacterial infections in febrile children. Sci Rep. 2019 Aug 13;9(1):11780. doi: 10.1038/s41598-019-48162-9. PMID: 31409879; PMCID: PMC6692396. |
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