Search by BoMiProt ID - Bomi8328


Primary Information

BoMiProt ID Bomi8328
Protein Name Protein FAM107B
Organism Bos taurus
Uniprot IdQ2KI00
Milk Fractionwhey
Ref Sequence Id NP_001039858.1
Aminoacid Length 131
Molecular Weight 15586
Fasta Sequence https://www.uniprot.org/uniprot/Q2KI00.fasta
Gene Name FAM107B
Gene Id 535023
Protein Existence Status Reviewed

Secondary Information

Protein Function Probably act as as a heat shock protein.
Biochemical Properties The Family with sequence similarity 107 (FAM107) possesses an N-terminal domain of unknown function (DUF1151) that is highly conserved beyond species and C-terminal (aa 61-112) variable coiled-coil region.Has a nuclear localization signal (NLS) in the center of the protein sequences.
PTMs Acetylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions (1-131)
DisProt Annotation
TM Helix Prediction No TM helices
Additional Comments FAM107B expression was decreased in stomach cancer and other cancers also.
Bibliography 1.Nakajima H, Ishigaki Y, Xia QS, Ikeda T, Yoshitake Y, Yonekura H, Nojima T, Tanaka T, Umehara H, Tomosugi N, Takata T, Shimasaki T, Nakaya N, Sato I, Kawakami K, Koizumi K, Minamoto T, Motoo Y. Induction of HITS, a newly identified family with sequence similarity 107 protein (FAM107B), in cancer cells by heat shock stimulation. Int J Oncol. 2010 Sep;37(3):583-93. doi: 10.3892/ijo_00000707. PMID: 20664927. 2.Guo, J., Bian, Y., Wang, Y., Chen, L., Yu, A., & Sun, X. (2017). FAM107B is regulated by S100A4 and mediates the effect of S100A4 on the proliferation and migration of MGC803 gastric cancer cells. Cell biology international, 41(10), 1103–1109. https://doi.org/10.1002/cbin.10816