Primary Information
BoMiProt ID	Bomi8294
Protein Name	Prostamide/prostaglandin F synthase/Peroxiredoxin-like 2B
Organism	Bos taurus
Uniprot ID	Q58CY6
Milk Fraction	Exosomes
Ref Sequence ID	NP_001035688.1
Aminoacid Length	201
Molecular Weight	21497
FASTA Sequence	Download
Gene Name	PRXL2B
Gene ID	617001
Protein Existence Status	Reviewed
Secondary Information
Protein Function	Prostamide/prostaglandin F synthase (PM/PGFS) is an enzyme with very narrow substrate specificity and is dedicated to the biosynthesis of prostamide F2α and prostaglandin F2α (PGF2α.).
PTMs	Phosphorylation at Tyr
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q58CY6|PXL2B_BOVIN Prostamide/prostaglandin F synthase OS=Bos taurus OX=9913 GN=PRXL2B PE=2 SV=1 MSTVDLARVGACVLKHAVTGEAVELRNLWQEQACVVAGLRRFGCMVCRWIARDLSNLKGL LDQHGVRLVGVGPEALGLQEFLDGGYFAGELYLDESKQFYKELGFKRY*108NSLSILPAALGK PVREVAAKAKAVGIQGNLSGDLLQSGGLLVVAKGGDKVLLHFVQKSPGDYAPLESILQAL GISAEVGPSELPQCDEEACSR
Predicted Disorder Regions	1-9, 186-201
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	1.Bertrand JA, Woodward DF, Sherwood JM, Spenlehauer A, Silvestri C, Piscitelli F, Marzo VD, Yamazaki M, Sakimura K, Inoue Y, Watanabe K, Overby DR. Deletion of the gene encoding prostamide/prostaglandin F synthase reveals an important role in regulating intraocular pressure. Prostaglandins Leukot Essent Fatty Acids. 2021 Feb;165:102235. doi: 10.1016/j.plefa.2020.102235. Epub 2021 Jan 5. PMID: 33418484. 2.