Primary Information |
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BoMiProt ID | Bomi8225 |
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Protein Name | Probable tubulin polyglutamylase TTLL9/Tubulin--tyrosine ligase-like protein 9 |
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Organism | Bos taurus |
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Uniprot Id | Q3SZH6 |
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Milk Fraction | Whey |
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Ref Sequence Id | NP_001030455.1 |
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Aminoacid Length | 461 |
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Molecular Weight | 54111 |
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Fasta Sequence | https://www.uniprot.org/uniprot/Q3SZH6.fasta |
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Gene Name | TTLL9 |
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Gene Id | 529246 |
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Protein Existence Status | reviewed |
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Secondary Information |
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Protein Function | generates side chains of glutamate on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of target proteins. |
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Biochemical Properties | acquire enzymatic activity only in complex with other proteins( FAP234).Mg2+ as cofactor. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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Predicted Disorder Regions | 1-21, 174-210, 414-428, 453-461 |
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DisProt Annotation | |
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TM Helix Prediction | No TM helices |
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Bibliography | Kubo T, Yanagisawa HA, Liu Z, Shibuya R, Hirono M, Kamiya R. A conserved flagella-associated protein in Chlamydomonas, FAP234, is essential for axonemal localization of tubulin polyglutamylase TTLL9. Mol Biol Cell. 2014 Jan;25(1):107-17. doi: 10.1091/mbc.E13-07-0424. Epub 2013 Nov 6. PMID: 24196831; PMCID: PMC3873882. |