Search by BoMiProt ID - Bomi8225


Primary Information

BoMiProt ID Bomi8225
Protein Name Probable tubulin polyglutamylase TTLL9/Tubulin--tyrosine ligase-like protein 9
Organism Bos taurus
Uniprot IdQ3SZH6
Milk FractionWhey
Ref Sequence Id NP_001030455.1
Aminoacid Length 461
Molecular Weight 54111
Fasta Sequence https://www.uniprot.org/uniprot/Q3SZH6.fasta
Gene Name TTLL9
Gene Id 529246
Protein Existence Status reviewed

Secondary Information

Protein Function generates side chains of glutamate on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of target proteins. 
Biochemical Properties  acquire enzymatic activity only in complex with other proteins( FAP234).Mg2+ as cofactor.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions 1-21, 174-210, 414-428, 453-461
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Kubo T, Yanagisawa HA, Liu Z, Shibuya R, Hirono M, Kamiya R. A conserved flagella-associated protein in Chlamydomonas, FAP234, is essential for axonemal localization of tubulin polyglutamylase TTLL9. Mol Biol Cell. 2014 Jan;25(1):107-17. doi: 10.1091/mbc.E13-07-0424. Epub 2013 Nov 6. PMID: 24196831; PMCID: PMC3873882.