Search by BoMiProt ID - Bomi8132


Primary Information

BoMiProt ID Bomi8132
Protein Name Polycomb complex protein BMI-1/Polycomb group RING finger protein 4
Organism Bos taurus
Uniprot IdQ32KX7
Milk FractionWhey
Ref Sequence Id NP_001033161.1
Aminoacid Length 326
Molecular Weight 36966
Fasta Sequence https://www.uniprot.org/uniprot/Q32KX7.fasta
Gene Name BMI1/PCGF4
Gene Id 510666
Protein Existence Status reviewed

Secondary Information

Protein Function Component of a Polycomb group (PcG) multiprotein PRC1-like complex, role in the regulation of Hox gene expression, X-chromosome inactivation, tumorigenesis, and stem cell self-renewal.monoubiquitination of histone H2A 'Lys-119'
PTMs ubl conjugation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions 102-122, 228-326
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Li Z, Cao R, Wang M, Myers MP, Zhang Y, Xu RM. Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex. J Biol Chem. 2006 Jul 21;281(29):20643-9. doi: 10.1074/jbc.M602461200. Epub 2006 May 18. PMID: 16714294.