Search by BoMiProt ID - Bomi7964


Primary Information

BoMiProt ID Bomi7964
Protein Name Phosphatidylserine lipase ABHD16A/Alpha/beta hydrolase domain-containing protein 16A/Abhydrolase domain-containing protein 16A/HLA-B-associated transcript 5 homolog/Monoacylglycerol lipase ABHD16A
Organism Bos taurus
Uniprot IdQ1JPD2
Milk FractionWhey,MFGM
Ref Sequence Id NP_001069073.1
Aminoacid Length 558
Molecular Weight 63304
Fasta Sequence https://www.uniprot.org/uniprot/Q1JPD2.fasta
Gene Name ABHD16A
Gene Id 513252
Protein Existence Status reviewed

Secondary Information

Protein Function These proteins could play an important role in the regulation of lipid metabolism and signalling transduction pathways, and are possibly directly or indirectly correlated with several human diseases.
Biochemical Properties ABHD16A has acylglycerol lipase and phosphatidylserine lipase activities.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction 2TMHs; (60-82), (95-117)
Additional Comments Other members of the ABHD protein family are associated with different diseases, such as cancer, lipid metabolism, liver disease and pulmonary disease.
Bibliography Xu J, Gu W, Ji K, Xu Z, Zhu H, Zheng W. Sequence analysis and structure prediction of ABHD16A and the roles of the ABHD family members in human disease. Open Biol. 2018 May;8(5):180017. doi: 10.1098/rsob.180017. PMID: 29794032; PMCID: PMC5990648.