Primary Information
BoMiProt ID	Bomi7903
Protein Name	Peroxisomal carnitine O-octanoyltransferase
Organism	Bos taurus
Uniprot ID	O19094
Milk Fraction	Whey
Ref Sequence ID	NP_803460.1
Aminoacid Length	612
Molecular Weight	70263
FASTA Sequence	Download
Gene Name	CROT/COT
Gene ID	281092
Protein Existence Status	reviewed
Secondary Information
Protein Function	Participate in beta-oxidation of fatty acids.
Biochemical Properties	transesterifies medium- and long-chain fatty acyl chains and belongs to a carnitine acyltransferase family that catalyzes a reversible reaction of L-carnitine + acyl-CoA ⇄ acyl-L-carnitine + CoASH.
PTMs	Acetylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	NA
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Okui T, Iwashita M, Rogers MA, Halu A, Atkins SK, Kuraoka S, Abdelhamid I, Higashi H, Ramsaroop A, Aikawa M, Singh SA, Aikawa E. CROT (Carnitine O-Octanoyltransferase) Is a Novel Contributing Factor in Vascular Calcification via Promoting Fatty Acid Metabolism and Mitochondrial Dysfunction. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):755-768. doi: 10.1161/ATVBAHA.120.315007. Epub 2020 Dec 24. PMID: 33356393; PMCID: PMC8105275.