Search by BoMiProt ID - Bomi7852


Primary Information

BoMiProt ID Bomi7852
Protein Name PCNA-associated factor
Organism Bos taurus
Uniprot IdQ5E9B2
Milk FractionWhey,exosome
Ref Sequence Id NP_001015678.1
Aminoacid Length 111
Molecular Weight 11910
Fasta Sequence https://www.uniprot.org/uniprot/Q5E9B2.fasta
Gene Name PCLAF
Gene Id 540737
Protein Existence Status reviewed

Secondary Information

Protein Function regulator of DNA repair during DNA replication. P15PAF (KIAA0101) was significantly upregulated in high-grade serous ovarian cancer (HGSOC).
PTMs Acetylation, Phosphorylation, Ubl conjugation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
>sp|Q5E9B2|PAF15_BOVIN PCNA-associated factor OS=Bos taurus OX=9913 GN=PCLAF PE=3 SV=1 MVRTKANS*8VPGSYRKVVASRAPRKVLGS*28STS*31AANSTPLSSRKAENKYAGGNPVCVRPTPK WQKGIGEFFSLS*72PKDSEKENRIPEEAGSSGLGKAKRKACPLPPDHTDDEKE
Predicted Disorder Regions 1 disordered segment; (1-111)
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Jin C, Liu Z, Li Y, Bu H, Wang Y, Xu Y, Qiu C, Yan S, Yuan C, Li R, Diao N, Zhang Z, Wang X, Liu L, Kong B. PCNA-associated factor P15PAF , targeted by FOXM1, predicts poor prognosis in high-grade serous ovarian cancer patients. Int J Cancer. 2018 Dec 1;143(11):2973-2984. doi: 10.1002/ijc.31800. Epub 2018 Oct 4. PMID: 30129654.