Search by BoMiProt ID - Bomi7741


Primary Information

BoMiProt ID Bomi7741
Protein Name Omega-amidase NIT2/Nitrilase homolog 2
Organism Bos taurus
Uniprot IdQ2T9R6
Milk FractionExosomes
Ref Sequence Id NP_001033222.1
Aminoacid Length 276
Molecular Weight 30518
Fasta Sequence https://www.uniprot.org/uniprot/Q2T9R6.fasta
Gene Name NIT2
Gene Id 520620
Protein Existence Status Reviewed

Secondary Information

Protein Function Nit2/ω-amidase catalyzes the hydrolysis of α-ketoglutaramate (KGM, the α-keto acid analogue of glutamine) to α-ketoglutarate and ammonia. The enzyme also catalyzes the amide hydrolysis of monoamides of 4- and 5-C-dicarboxylates, including α-ketosuccinamate (KSM, the α-keto acid analogue of asparagine) and succinamate (SM). 
PTMs N6-acetylation at Lysine
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.Epova EY, Shevelev AB, Shurubor YI, Cooper AJL, Biryukova YK, Bogdanova ES, Tyno YY, Lebedeva AA, Krasnikov BF. A novel efficient producer of human ω-amidase (Nit2) in Escherichia coli. Anal Biochem. 2021 Nov 1;632:114332. doi: 10.1016/j.ab.2021.114332. Epub 2021 Aug 12. PMID: 34391728. 2.