Primary Information |
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| BoMiProt ID | Bomi7463 |
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| Protein Name | Neuron-specific calcium-binding protein hippocalcin |
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| Organism | Bos taurus |
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| Uniprot ID | Q4PL64 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001020499.1 |
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| Aminoacid Length | 193 |
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| Molecular Weight | 22427 |
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| FASTA Sequence |
Download |
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| Gene Name | HPCA |
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| Gene ID | 509772 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels. |
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| Biochemical Properties | is an EF-hand Ca2+ binding protein |
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| PTMs | Myristoylation,Lipidation. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | 3-26, 37-46, 51-159, 176-193 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Significance of PTMs | Hippocalcin are myristylated at their N-termini, which is important for Ca2+-dependent membrane association. |
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| Bibliography | Kikuchi T, Ichikawa M, Arai J, Tateiwa H, Fu L, Higuchi K, Yoshimura N. Molecular cloning and characterization of a new neuron-specific homologue of rat polypyrimidine tract binding protein. J Biochem. 2000 Nov;128(5):811-21. doi: 10.1093/oxfordjournals.jbchem.a022819. PMID: 11056394. |
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