Biochemical Properties | exist as homo- or heteromeric complexes; presence of three PA28 homologs, called α,ß and ɣ; α and ß subunits form a heteroheptamer, whereas ɣ forms
a homoheptamer; PA28 was purified
from extracts of rat liver, which had high levels of
PA28 protein but no PA28 activity; Carboxypeptidase inactivates
PA28; bovine PA28 contain a 'KEKE motif', which is characterized by a high content of alternating lysine and glutamic acid
residues; |
---|
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