Search by BoMiProt ID - Bomi7345


Primary Information

BoMiProt ID Bomi7345
Protein Name N-acetylneuraminate lyase/N-acetylneuraminate pyruvate-lyase/N-acetylneuraminic acid aldolase/Sialate lyase/Sialate-pyruvate lyase/Sialic acid aldolase/Sialic acid lyase
Organism Bos taurus
Uniprot IdQ29RY9
Milk FractionWhey
Ref Sequence Id NP_001039443.1
Aminoacid Length 320
Molecular Weight 35166
Fasta Sequence https://www.uniprot.org/uniprot/Q29RY9.fasta
Gene Name NPL
Gene Id 507597
Protein Existence Status reviewed

Secondary Information

Protein Function Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions 1-8, 314-320
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Uchida Y, Tsukada Y, Sugimori T. Purification and properties of N-acetylneuraminate lyase from Escherichia coli. J Biochem. 1984 Aug;96(2):507-22. doi: 10.1093/oxfordjournals.jbchem.a134863. PMID: 6389524.