Search by BoMiProt ID - Bomi7323


Primary Information

BoMiProt ID Bomi7323
Protein Name N(G),N(G)-dimethylarginine dimethylaminohydrolase 2/Dimethylargininase-2/DDAHII
Organism Bos taurus
Uniprot IdQ3SX44
Milk FractionWhey
Ref Sequence Id NP_001029876.1
Aminoacid Length 285
Molecular Weight 29780
Fasta Sequence https://www.uniprot.org/uniprot/Q3SX44.fasta
Gene Name DDAH2
Gene Id 540386
Protein Existence Status reviewed

Secondary Information

Protein Function It regultes nitric oxide metabolism by Hydrolyzing N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA).
Biochemical Properties H2O + Nω,Nω-dimethyl-L-arginine = dimethylamine + L-citrulline
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions (2-11), (26-32), (92-96), (233-241)
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Zhou, Q., Chen, S., Li, H., Yang, B., Chen, T., Hu, T., Yin, D., He, H., & He, M. (2020). Tetramethylpyrazine alleviates iron overload damage in vascular endothelium via upregulating DDAHII expression. Toxicology in vitro : an international journal published in association with BIBRA, 65, 104817. https://doi.org/10.1016/j.tiv.2020.104817