Primary Information |
---|
BoMiProt ID | Bomi7202 |
---|
Protein Name | MOB kinase activator 3B/Mob1 homolog 2b/Mps one binder kinase activator-like 2B |
---|
Organism | Bos taurus |
---|
Uniprot ID | Q29RK9 |
---|
Milk Fraction | Exosomes |
---|
Ref Sequence ID | NP_001039956.1 |
---|
Aminoacid Length | 216 |
---|
Molecular Weight | 25450 |
---|
FASTA Sequence |
Download |
---|
Gene Name | MOB3B |
---|
Gene ID | 540817 |
---|
Protein Existence Status | Reviewed |
---|
Secondary Information |
---|
Presence in other biological fluids/tissue/cells | pons |
---|
Protein Function | MOB proteins are integral components of signaling pathways controlling important cellular processes, such as mitotic exit, centrosome duplication, apoptosis, and cell proliferation in eukaryotes. |
---|
Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
---|
Predicted Disorder Regions | (1-34) |
---|
DisProt Annotation | |
---|
TM Helix Prediction | No TM helices |
---|
Additional Comments | overexpression of hMOB3 proteins did not significantly affect centrosome duplication, a known function of NDR1/2 kinases |
---|
Bibliography | 1.Kohler RS, Schmitz D, Cornils H, Hemmings BA, Hergovich A. Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases. Mol Cell Biol. 2010 Sep;30(18):4507-20. doi: 10.1128/MCB.00150-10. Epub 2010 Jul 12. PMID: 20624913; PMCID: PMC2937529. |