Search by BoMiProt ID - Bomi7202


Primary Information

BoMiProt ID Bomi7202
Protein Name MOB kinase activator 3B/Mob1 homolog 2b/Mps one binder kinase activator-like 2B
Organism Bos taurus
Uniprot IdQ29RK9
Milk FractionExosomes
Ref Sequence Id NP_001039956.1
Aminoacid Length 216
Molecular Weight 25450
Fasta Sequence https://www.uniprot.org/uniprot/Q29RK9.fasta
Gene Name MOB3B
Gene Id 540817
Protein Existence Status Reviewed

Secondary Information

Presence in other biological fluids/tissue/cells pons
Protein Function MOB proteins are integral components of signaling pathways controlling important cellular processes, such as mitotic exit, centrosome duplication, apoptosis, and cell proliferation in eukaryotes. 
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions (1-34)
DisProt Annotation
TM Helix Prediction No TM helices
Additional Comments overexpression of hMOB3 proteins did not significantly affect centrosome duplication, a known function of NDR1/2 kinases
Bibliography 1.Kohler RS, Schmitz D, Cornils H, Hemmings BA, Hergovich A. Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases. Mol Cell Biol. 2010 Sep;30(18):4507-20. doi: 10.1128/MCB.00150-10. Epub 2010 Jul 12. PMID: 20624913; PMCID: PMC2937529.