Primary Information |
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| BoMiProt ID | Bomi7158 |
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| Protein Name | Mitoferrin-1/Mitochondrial iron transporter 1/Solute carrier family 25 member 37 |
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| Organism | Bos taurus |
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| Uniprot ID | Q3ZBJ8 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001029721.1 |
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| Aminoacid Length | 171 |
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| Molecular Weight | 18492 |
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| FASTA Sequence |
Download |
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| Gene Name | SLC25A37/MFRN |
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| Gene ID | 523756 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | helps in iron uptake,essential role in heme biosynthesis.mitochondrial iron homeostasis. |
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| Biochemical Properties | 38 kDa protein |
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| Significance in milk | Iron Regulation and immunometabolism |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | 3 disordered segments; (1-52), (138-142), (158-171) |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | Paradkar PN, Zumbrennen KB, Paw BH, Ward DM, Kaplan J. Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2. Mol Cell Biol. 2009 Feb;29(4):1007-16. doi: 10.1128/MCB.01685-08. Epub 2008 Dec 15. PMID: 19075006; PMCID: PMC2643804. |
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