Search by BoMiProt ID - Bomi7148


Primary Information

BoMiProt ID Bomi7148
Protein Name Mitochondrial import receptor subunit TOM40 homolog/Translocase of outer membrane 40 kDa subunit homolog
Organism Bos taurus
Uniprot IdQ1LZB5
Milk FractionWhey,MFGM
Ref Sequence Id NP_001068906.1
Aminoacid Length 361
Molecular Weight 37725
Fasta Sequence https://www.uniprot.org/uniprot/Q1LZB5.fasta
Gene Name TOMM40
Gene Id 510219
Protein Existence Status Reviewed

Secondary Information

Protein Function Channel-forming protein essential for import of protein precursors into mitochondria. Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) 
PTMs N-myristoylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions (4-80)
DisProt Annotation
TM Helix Prediction No TM helices
Significance of PTMs role in the mitochondrial targeting
Bibliography Soyal, S. M., Kwik, M., Kalev, O., Lenz, S., Zara, G., Strasser, P., Patsch, W., & Weis, S. (2020). A TOMM40/APOE allele encoding APOE-E3 predicts high likelihood of late-onset Alzheimer's disease in autopsy cases. Molecular genetics & genomic medicine, 8(8), e1317. https://doi.org/10.1002/mgg3.1317