Search by BoMiProt ID - Bomi7145


Primary Information

BoMiProt ID Bomi7145
Protein Name Mitochondrial import inner membrane translocase subunit Tim22
Organism Bos taurus
Uniprot IdQ5BIN4
Milk FractionWhey
Ref Sequence Id NP_001029670.1
Aminoacid Length 194
Molecular Weight 20156
Fasta Sequence https://www.uniprot.org/uniprot/Q5BIN4.fasta
Gene Name TIMM22/TIM22
Gene Id 515555
Protein Existence Status reviewed

Secondary Information

Protein Function It is an essential and indispensable component of the TIM22 complex
PTMs Disulphide bonds
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions 1-22, 39-55,
DisProt Annotation
TM Helix Prediction 1TMH; (70-92)
Significance of PTMs These bonds ensure that TIM22 complex is assembled efficiently.
Bibliography Vukotic, M., Nolte, H., König, T., Saita, S., Ananjew, M., Krüger, M., Tatsuta, T., & Langer, T. (2017). Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria. Molecular cell, 67(3), 471–483.e7. https://doi.org/10.1016/j.molcel.2017.06.013