Search by BoMiProt ID - Bomi7043


Primary Information

BoMiProt ID Bomi7043
Protein Name Methenyltetrahydrofolate synthase domain-containing protein
Organism Bos taurus
Uniprot IdQ2KI24
Milk FractionWhey
Ref Sequence Id NP_001039507.1
Aminoacid Length 380
Molecular Weight 41483
Fasta Sequence https://www.uniprot.org/uniprot/Q2KI24.fasta
Gene Name MTHFSD
Gene Id 509897
Protein Existence Status reviewed

Secondary Information

Protein Function RNA binding proteins.MTHFSD is a component of stress granules induced by oxidative stress
Biochemical Properties contains a RRM domain, common among ALS-related proteins and components of stress granules
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions 250-257, 269-281, 358-380
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.MacNair L, Xiao S, Miletic D, Ghani M, Julien JP, Keith J, Zinman L, Rogaeva E, Robertson J. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis. Brain. 2016 Jan;139(Pt 1):86-100. doi: 10.1093/brain/awv308. Epub 2015 Nov 2. PMID: 26525917.