Primary Information
BoMiProt ID	Bomi6767
Protein Name	Leucine-rich repeat and fibronectin type-III domain-containing protein 3/Synaptic adhesion-like molecule 4
Organism	Bos taurus
Uniprot ID	Q1RMS4
Milk Fraction	Whey
Ref Sequence ID	NP_001070427.1
Aminoacid Length	628
Molecular Weight	66260
FASTA Sequence	Download
Gene Name	LRFN3/SALM4
Gene ID	767839
Protein Existence Status	reviewed
Secondary Information
Protein Function	Cell adhesion molecule mediating cell-cell adhesion in a Ca2+-independent manner. Promotes neurite outgrowth in hippocampal neurons.
PTMs	Disulphide bond, Glycosylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q1RMS4|LRFN3_BOVIN Leucine-rich repeat and fibronectin type-III domain-containing protein 3 OS=Bos taurus OX=9913 GN=LRFN3 PE=2 SV=1 MAVLPLLLCLLPLAPASSPPQPASPSPCPRRCRCQTQSLPLSVLCPGAGLLFVPPSLDRR AAELRLADNFIATVRRRDLANMTGLLHLSLSRNTIRHVAAGAFSDLRALRALHLDGNRLT SLGEGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNNLEQLPWEALGRLG NVNTLGLDHNLLASVPAGAFSRLHKLARLDMTSNRLTTIPPDPLFSRLPLLARPRGSPAS ALVLAFGGNPLHCNCELVWLRRLAREDDLEACASPPALGGRYFWAVGEEEFVCEPPVVTH RSPPLAVPAGRPAALRCRAVGDPEPRVRWVSPQGRLLGNSSRARAFPN*348GTLELLVTEPGD GGIFTCIAANAAGEATAAVELTVGPPPPPQLAN*393STSCDPPRDGEPDALTPPSAASASASA KAAEAGPPTDRGVQVTEHGATAALIQWPDQRPIPGIRMYQIQYNSSADDILVYRMIPAES SSFLLTDLASGRTYDLCVLAVYEDSATGLTATRPVGCNRFSTEPALRPCGAPHAPFLGGT MIIALGGVIVASVLVFIFVLLMRYKVHGGQPPGKTKASAPVSSVCSQTNGALGPMPAPPA PEPSAPRAHTVVQLDCEPWGPSHEPMGP
Predicted Disorder Regions	(20-26), (384-428), (522-526), (569-628)
DisProt Annotation
TM Helix Prediction	1TMH; (539-561)
Significance of PTMs	N-glycosylated.
Bibliography	Bovine Genome Sequencing and Analysis Consortium, Elsik, C. G., Tellam, R. L., Worley, K. C., Gibbs, R. A., Muzny, D. M., Weinstock, G. M., Adelson, D. L., Eichler, E. E., Elnitski, L., Guigó, R., Hamernik, D. L., Kappes, S. M., Lewin, H. A., Lynn, D. J., Nicholas, F. W., Reymond, A., Rijnkels, M., Skow, L. C., Zdobnov, E. M., … Zhao, F. Q. (2009). The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science (New York, N.Y.), 324(5926), 522–528. https://doi.org/10.1126/science.1169588