Search by BoMiProt ID - Bomi6665


Primary Information

BoMiProt ID Bomi6665
Protein Name Kinesin-like protein KIF3C
Organism Bos taurus
Uniprot IdA0JN40
Milk FractionWhey,exosome
Ref Sequence Id NP_001071623.1
Aminoacid Length 792
Molecular Weight 89487
Fasta Sequence https://www.uniprot.org/uniprot/A0JN40.fasta
Gene Name KIF3C
Gene Id 777770
Protein Existence Status reviewed

Secondary Information

Protein Function KIF3C is a novel kinesin-like protein that might be specifically involved in microtubule-based transport in neuronal cells.
Biochemical Properties Sequence and secondary structure analysis suggests that KIF3C is a new member of the KIF3 family. However, in contrast to KIF3A and KIF3B, KIF3C is mainly expressed in neural tissues.
PTMs N6-acetylation at Lysine
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Additional Comments KIF3C has a high probability of forming an a coiled-coil structure from residues 455 to 633, suggesting that native KIF3C may be form a dimer via interactions within this region.
Bibliography 1.Sardella M, Navone F, Rocchi M, Rubartelli A, Viggiano L, Vignali G, Consalez GG, Sitia R, Cabibbo A. KIF3C, a novel member of the kinesin superfamily: sequence, expression, and mapping to human chromosome 2 at 2p23. Genomics. 1998 Feb 1;47(3):405-8. doi: 10.1006/geno.1997.5123. PMID: 9480755. 2.Yang Z, Goldstein LS. Characterization of the KIF3C neural kinesin-like motor from mouse. Mol Biol Cell. 1998 Feb;9(2):249-61. doi: 10.1091/mbc.9.2.249. PMID: 9450952; PMCID: PMC25248.