Search by BoMiProt ID - Bomi6526


Primary Information

BoMiProt ID Bomi6526
Protein Name Isovaleryl-CoA dehydrogenase, mitochondrial/Butyryl-CoA dehydrogenase/IVD
Organism Bos taurus
Uniprot IdQ3SZI8
Milk FractionWhey
Ref Sequence Id NP_001029554.1
Aminoacid Length 426
Molecular Weight 46498
Fasta Sequence https://www.uniprot.org/uniprot/Q3SZI8.fasta
Gene Name IVD
Gene Id 510440
Protein Existence Status reviewed

Secondary Information

Protein Function intramitochondrial homotetrameric flavoenzyme in the leucine catabolism pathway.
Biochemical Properties It is a homotetramer.Cofactor is FAD.It catalyzes the conversion of 3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA as an intermediate step in the leucine catabolic pathway. It is also able to catalyze the oxidation of other saturated short-chain acyl-CoA thioesters as pentanoyl-CoA, hexenoyl-CoA and butenoyl-CoA..
PTMs Acetylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Schilling, B., Murray, J., Yoo, C. B., Row, R. H., Cusack, M. P., Capaldi, R. A., & Gibson, B. W. (2006). Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria. Biochimica et biophysica acta, 1762(2), 213–222. https://doi.org/10.1016/j.bbadis.2005.07.003