Primary Information |
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| BoMiProt ID | Bomi6439 |
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| Protein Name | Integrin beta-5 |
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| Organism | Bos taurus |
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| Uniprot Id | P80747 |
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| Milk Fraction | Whey |
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| Aminoacid Length | 800 |
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| Molecular Weight | 88057 |
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| Fasta Sequence | https://www.uniprot.org/uniprot/P80747.fasta |
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| Gene Name | ITGB5 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Presence in other biological fluids/tissue/cells | Endothelial cells |
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| Protein Function | cell to ECM attachment.binds to fibronectin at RGD sequence |
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| PTMs | phosphorylation on Ser |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|P80747|ITB5_BOVIN Integrin beta-5 OS=Bos taurus OX=9913 GN=ITGB5 PE=1 SV=2
MPRAPALLFSCLLGLCALVPRLPGLNICTSGSATSCEECLLIHPKCAWCFKEDFGSLRSV
TSRCDLKANLIRNGCGVEFESPASSTQVLRSLPLSSKGSSPAGSDVIQLTPQEVTVTLRP
GDRTAFQLQVRQVEDYPVDLYYLMDLSLSMKDDLENIRSLGTKLAEEMRKLTSNFRLGFG
SFVDKNISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC
HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKN*347FTALIPGTTVEIL
HGDSKNILQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGD
TASFEVSVEARSCPSKHVQHTFTLRPVGFRDSLEVGVTYNCRCGCSAGLEPDSARCSSN*479G
TYVCGLCECNPGYLGTRCECQEGESQSGYQNLCREAEGKPLCSGRGQCSCNQCSCFESEF
GKIYGSFCECDN*552FSCARNKGVLCSGHGECHCGECKCHAGYIGDNCN*586CSTDISTCQARDGH
ICSDRGHCVCGQCQCTEPGAFGETCEKCPTCPDACSTKRDCVECLLLHSGSSADN*655QTCQN
LCKDEVITRVDTIVKDDQEAVLCFYKTAKDCVMMFTYSELPSGKSN*706LTVLREPECGTAPS
AMTILLAVVGSILLTGFALLVIWKLLVTIHDRREFAKFQSERSRARYEMAS*771NPLYRKPIS
THTVDFTFNKFNKSYNGTVD
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | 1TMH; (721-743) |
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| Bibliography | Zhang LY, Guo Q, Guan GF, Cheng W, Cheng P, Wu AH. Integrin Beta 5 Is a Prognostic Biomarker and Potential Therapeutic Target in Glioblastoma. Front Oncol. 2019 Sep 20;9:904. doi: 10.3389/fonc.2019.00904. PMID: 31616629; PMCID: PMC6764112. |
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