Search by BoMiProt ID - Bomi6388


Primary Information

BoMiProt ID Bomi6388
Protein Name Inactive hydroxysteroid dehydrogenase-like protein 1
Organism Bos taurus
Uniprot IdA5PJF6
Milk FractionWhey
Ref Sequence Id NP_001092341.1
Aminoacid Length 330
Molecular Weight 37014
Fasta Sequence https://www.uniprot.org/uniprot/A5PJF6.fasta
Gene Name HSDL1
Gene Id 505213
Protein Existence Status reviewed

Secondary Information

Protein Function  highly expressed in testis and ovary
Biochemical Properties  309 amino acid long.Human HSDL1 has a tyr218-to-phe (Y218F) substitution in its catalytic motif, suggesting that it is inactive, and this substitution is conserved in rodents, cattle, and zebrafish.
PTMs Acetylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Huang Y, Tang R, Dai J, Gu S, Zhao W, Cheng C, Xu M, Zhou Z, Ying K, Xi Y, Mao Y. A novel human hydroxysteroid dehydrogenase like 1 gene (HSDL1) is highly expressed in reproductive tissues. Mol Biol Rep. 2001;28(4):185-91. doi: 10.1023/a:1015726217890. PMID: 12153137.