Primary Information
BoMiProt ID	Bomi634
Protein Name	C4b-binding protein alpha chain
Organism	Bos taurus
Uniprot ID	Q28065
Milk Fraction	Whey
Ref Sequence ID	NP_776677.1
Aminoacid Length	610
Molecular Weight	68886
FASTA Sequence	Download
Gene Name	C4BPA
Gene ID	281651
Protein Existence Status	Reveiwed;Experimental evidence at transcript level
Secondary Information
Protein Function	C4b-binding protein α-chain (C4BPA) as a serum biomarker for the early detection of pancreatic ductal adenocarcinoma (PDAC).
PTMs	Disulfide bond formation,N-Linked Glycosylation at Asn
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	1.Sasaki K, Takano S, Tomizawa S, Miyahara Y, Furukawa K, Takayashiki T, Kuboki S, Takada M, Ohtsuka M. C4b-binding protein α-chain enhances antitumor immunity by facilitating the accumulation of tumor-infiltrating lymphocytes in the tumor microenvironment in pancreatic cancer. J Exp Clin Cancer Res. 2021 Jun 24;40(1):212. doi: 10.1186/s13046-021-02019-0. PMID: 34167573; PMCID: PMC8228942.