Search by BoMiProt ID - Bomi6283


Primary Information

BoMiProt ID Bomi6283
Protein Name Histone H1.8/Histone H1oo/Oocyte-specific histone H1/Oocyte-specific linker histone H1
Organism Bos taurus
Uniprot IdQ3HNG7
Milk FractionWhey
Ref Sequence Id NP_001030449.1
Aminoacid Length 343
Molecular Weight 35436
Fasta Sequence https://www.uniprot.org/uniprot/Q3HNG7.fasta
Gene Name H1-8/H1FOO
Gene Id 527400
Protein Existence Status reviewed

Secondary Information

Protein Function inhibits condensins and topo II to shape mitotic chromosome organization.
Significance in milk Bovine implantation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions 3 disordered segments; (1-56), (70-72), (110-343)
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Choppakatla P, Dekker B, Cutts EE, Vannini A, Dekker J, Funabiki H. Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization. Elife. 2021 Aug 18;10:e68918. doi: 10.7554/eLife.68918. PMID: 34406118; PMCID: PMC8416026.