Primary Information
BoMiProt ID	Bomi6154
Protein Name	GTPase Era, mitochondrial/ERA-like protein 1
Organism	Bos taurus
Uniprot ID	A5PK43
Milk Fraction	Whey
Ref Sequence ID	NP_001092492.1
Aminoacid Length	437
Molecular Weight	48567
FASTA Sequence	Download
Gene Name	ERAL1
Gene ID	523344
Protein Existence Status	reviewed
Secondary Information
Protein Function	Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly
PTMs	Phosphorylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|A5PK43|ERAL1_BOVIN GTPase Era, mitochondrial OS=Bos taurus OX=9913 GN=ERAL1 PE=2 SV=1 MAASSWRGAVLLRTVSGLWQAGPDAAREWMTRLPSLLGFQQRCVSCVAGPAFSGPRLASA SRPNGQNSALDCFLGLSQPDNSLPFRVPAVSVHRDEQDLLLVHRPDMPENPRVLRVVLLG APNAGKSTLSNQLLGRKVFPVSKKVHTTRSQALGVITEKETQVILLDTPGLIS*173PAKQKRH HLELSLLEDPWKSMESADLVVVLVDVSDKWTRNQLSPQVLRCLTQFSQVPSILVMNKVDC LKQKSVLLELTAALTEGVVNGKKLKTKQALRSRPDTHCPSPAAQGPNPQPVRDPQQMGWP HFQEIFMLSALSQEDVKTLKQYLLAQARPGPWEFHSEVLTSQTPEEICANMIREKLLEYL PEEVPYNVQQKTVVWDEGPSGELVIEQKLLVSKESHMKILIGPKGYLIAQIAQEVGRDLM NIFLCEVQLRLSVKLLK
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Dennerlein, S., Rozanska, A., Wydro, M., Chrzanowska-Lightowlers, Z. M., & Lightowlers, R. N. (2010). Human ERAL1 is a mitochondrial RNA chaperone involved in the assembly of the 28S small mitochondrial ribosomal subunit. The Biochemical journal, 430(3), 551–558. https://doi.org/10.1042/BJ20100757