Search by BoMiProt ID - Bomi5954


Primary Information

BoMiProt ID Bomi5954
Protein Name GATA zinc finger domain-containing protein 1
Organism Bos taurus
Uniprot IdA2VDY6
Milk FractionWhey
Ref Sequence Id NP_001075092.1
Aminoacid Length 272
Molecular Weight 28884
Fasta Sequence https://www.uniprot.org/uniprot/A2VDY6.fasta
Gene Name GATAD1
Gene Id 784921
Protein Existence Status reviewed

Secondary Information

Protein Function GATAD1 binds to a histone modification site that regulates gene expression.
PTMs Acetylation, isopeptide bond formation, Ubiquitinylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions (1-127)
DisProt Annotation
TM Helix Prediction No TM helices
Significance of PTMs acetylation may be required for chromatin occupancy
Bibliography 1.Lamonica, J. M., Vakoc, C. R., & Blobel, G. A. (2006). Acetylation of GATA-1 is required for chromatin occupancy. Blood, 108(12), 3736–3738. https://doi.org/10.1182/blood-2006-07-032847 2.Sun, W., Zhang, Y., Wong, K. C., Liu, K., Yang, Y., Wu, B., Tong, J., Chan, A., Chan, H., & Yu, J. (2018). Increased expression of GATA zinc finger domain containing 1 through gene amplification promotes liver cancer by directly inducing phosphatase of regenerating liver 3. Hepatology (Baltimore, Md.), 67(6), 2302–2319. https://doi.org/10.1002/hep.29750