Primary Information
BoMiProt ID	Bomi5937
Protein Name	Gap junction alpha-3 protein/Connexin-44/Cx44
Organism	Bos taurus
Uniprot ID	P41987
Milk Fraction	Whey
Ref Sequence ID	NP_001159768.1
Aminoacid Length	407
Molecular Weight	43611
FASTA Sequence	Download
Gene Name	GJA3
Protein Existence Status	reviewed
Secondary Information
Protein Function	It is a structural component of gap junctions in lens fiber.
PTMs	Disuphide bond, Phosophorylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	NA
Predicted Disorder Regions	(107-129), (233-406)
DisProt Annotation
TM Helix Prediction	4TMHs ; (20-38), (77-99), (144-166), (199-221)
Significance of PTMs	Phosphorylated on multiple threonine and serine residues. Phosphorylation may have a role in assembling connexins into connexons and gap junctional plaques, as well as channel gating
Bibliography	Gupta, V. K., Berthoud, V. M., Atal, N., Jarillo, J. A., Barrio, L. C., & Beyer, E. C. (1994). Bovine connexin44, a lens gap junction protein: molecular cloning, immunologic characterization, and functional expression. Investigative ophthalmology & visual science, 35(10), 3747–3758.