Search by BoMiProt ID - Bomi5871


Primary Information

BoMiProt ID Bomi5871
Protein Name FXYD domain-containing ion transport regulator 6/Phosphohippolin
Organism Bos taurus
Uniprot IdQ3MHZ5
Milk FractionWhey
Ref Sequence Id NP_001029571.1
Aminoacid Length 95
Molecular Weight 10465
Fasta Sequence https://www.uniprot.org/uniprot/Q3MHZ5.fasta
Gene Name FXYD6
Gene Id 511064
Protein Existence Status reviewed

Secondary Information

Protein Function FXYD6 is a novel regulator of Na,K-ATPase expressed in the inner ear
Biochemical Properties Most characterized FXYD proteins exhibit a similar structure with a single transmembrane domain and a type I orientation that is achieved, in some but not all cases, by the cleavage of an N-terminal signal peptide.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions 2 disordered segments; (19-29), (65-95)
DisProt Annotation
TM Helix Prediction 2TMHs;(3-21) and (36-58)
Bibliography Delprat B, Schaer D, Roy S, Wang J, Puel JL, Geering K. FXYD6 is a novel regulator of Na,K-ATPase expressed in the inner ear. J Biol Chem. 2007 Mar 9;282(10):7450-6. doi: 10.1074/jbc.M609872200. Epub 2007 Jan 5. PMID: 17209044.